Biodistribution and safety studies of a bicistronic plasmid 

Biodistribution and security research of a bicistronic plasmid for nerve restore

Background: Gene remedy is one of many promising approaches for regenerative drugs. Native and long-term expression of important progress elements permits to realize the specified therapeutic impact. Nonetheless, some features of extended utilization of genetic constructs encoding progress elements, resembling toxicity, mutagenicity, genotoxicity and talent to disseminate from the injection web site and mediate ectopic expression of therapeutic proteins, are poorly investigated. These features of gene remedy medication utilization turned the topic of this examine. Experiment: To check plasmid biodistribution, toxicity, mutagenicity and genotoxicity we used beforehand described bicistronic genetic assemble encoding human mind neurotrophic issue (hBDNF) and urokinase plasminogen activator (huPA) for nerve restore. Biodistribution research had been carried out in mice: a course of intramuscular plasmid injections was adopted by the examine of the content material of the plasmid (Actual-time PCR) and recombinant proteins (ELISA) in murine organs and tissues. The examine of the plasmid continual toxicity was carried out on rats with registration of their weight dynamics, neurological standing, emotional state and blood assessments parameters. The mutagenicity of the plasmid was studied in an in vivo DNA comet take a look at in mice. Plasmid genotoxicity was investigated within the mannequin of somatic recombination in Drosophila females.

Outcomes: We’ve proven that plasmids can disseminate from the injection web site, however don’t mediate ectopic expression of progress elements upon repeated intramuscular injections. The studied plasmid additionally does not reveal poisonous, mutagenic or genotoxic results. Throughout the toxicological examine on rats, we’ve got proven that every day injections of this genetic assemble, regardless of its skill to disseminate from the injection web site, do not have an effect on the bodily, cognitive and emotional state of experimental animals.

Conclusions: We’ve demonstrated the security of the bicistronic plasmid, encoding hBDNF and huPA, upon its repeated administration. The properties of genetic constructs strongly depend upon their sequence and supply strategy, which requires conducting of their security research in every particular case.

msc-alff
msc-alff

Human Nuclear pore membrane glycoprotein 210 (NUP210)

1-CSB-EP016195HU(C)
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Nuclear pore membrane glycoprotein 210(NUP210),partial expressed in E.coli

Human Tenascin (TNC)

1-CSB-RP115094h(C)
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Tenascin(TNC),partial expressed in E.coli

Human Antigen KI-67 (MKI67)

1-CSB-RP116174h(c)
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Antigen KI-67(MKI67) ,partial expressed in E.coli

Helicobacter pylori Vacuolating cytotoxin autotransporter (vacA)

1-CSB-RP143794Ba(C)
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Helicobacter pylori Vacuolating cytotoxin autotransporter(vacA),partial expressed in E.coli

Human Glutamyl aminopeptidase (ENPEP)

1-CSB-RP147594h(c)
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Glutamyl aminopeptidase(ENPEP),partial expressed in E.coli

Saccharomyces cerevisiae Trehalose-phosphatase (TPS2)

1-CSB-RP165694Ye(c)
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Saccharomyces cerevisiae Trehalose-phosphatase(TPS2),partial expressed in E.coli

Mouse Protein Muc5ac (Muc5ac)

1-CSB-RP172294m(C)
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Protein Muc5ac(Muc5ac),partial expressed in E.coli

Human Histone deacetylase 7 (HDAC7)

1-CSB-RP178994h(C)
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Histone deacetylase 7(HDAC7),partial expressed in E.coli

Human Telomerase protein component 1 (TEP1)

1-CSB-RP180494h(c)
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Telomerase protein component 1(TEP1),partial expressed in E.coli

Human Collagen alpha-1 (XVII) chain (COL17A1)

1-CSB-RP180994h(c)
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Collagen alpha-1(XVII) chain(COL17A1),partial expressed in E.coli

Saccharomyces cerevisiae Neutral trehalase (NTH1)

1-CSB-RP181594Ye(c)
  • EUR 733.20
  • EUR 370.80
  • EUR 2192.40
  • EUR 1126.80
  • EUR 1461.60
  • EUR 476.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Saccharomyces cerevisiae Neutral trehalase(NTH1),partial expressed in E.coli

pET-(-30)GFP-9xGGS-Cre-6xHis Plasmid

PVT17107 2 ug
EUR 390

SARS-CoV-2 Nucleocapsid Protein, Avi-His-tag

E80027
  • EUR 635.80
  • EUR 4087.60
  • 1 ml
  • 100 ul

Recombinant SARS-CoV-2 Spike Glycoprotein(S) (D614G), Partial

E80028
  • EUR 388.30
  • EUR 860.20
  • 20 ul
  • 100 ul

Recombinant Thermobifida Fusca Cutinase(C-6xHis)

CR10-10ug 10ug
EUR 242.4
Description: Supplied as a 0.2 μm filtered solution of 10mM Tris-HCl,1mM 2-mercaptoethanol,2mM MnCl2,150mM NaCl,pH7.5.

Recombinant Thermobifida Fusca Cutinase(C-6xHis)

CR10-1mg 1mg
EUR 2983.2
Description: Supplied as a 0.2 μm filtered solution of 10mM Tris-HCl,1mM 2-mercaptoethanol,2mM MnCl2,150mM NaCl,pH7.5.

Recombinant Thermobifida Fusca Cutinase(C-6xHis)

CR10-500ug 500ug
EUR 2106
Description: Supplied as a 0.2 μm filtered solution of 10mM Tris-HCl,1mM 2-mercaptoethanol,2mM MnCl2,150mM NaCl,pH7.5.

Recombinant Thermobifida Fusca Cutinase(C-6xHis)

CR10-50ug 50ug
EUR 595.2
Description: Supplied as a 0.2 μm filtered solution of 10mM Tris-HCl,1mM 2-mercaptoethanol,2mM MnCl2,150mM NaCl,pH7.5.

SARS-CoV-2 Spike S1 RBD Protein, Avi-His-tag

E80024
  • EUR 635.80
  • EUR 4995.10
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 RBD Protein, Mouse Fc-fusion

E80026
  • EUR 588.50
  • EUR 823.90
  • 20 ul
  • 50 ul

SARS-CoV-2 Spike S1 (16-685) Protein, Avi-His-tag

E80021
  • EUR 635.80
  • EUR 4276.80
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 RBD (V367F) Protein, Avi-His-tag

E80023
  • EUR 635.80
  • EUR 3934.70
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 (13-665) Protein, Fc Fusion, Avi-tag

E80020
  • EUR 635.80
  • EUR 4276.80
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 (16-685) Protein, Fc Fusion, Avi-tag

E80022
  • EUR 635.80
  • EUR 4276.80
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag

E80025
  • EUR 635.80
  • EUR 3934.70
  • 100 ul
  • 1 ml

pLenti-CARM1 shRNA-2 Plasmid

PVTBAV03691-2 2 ug
EUR 427.2

pLenti-CTLA4 shRNA-2 Plasmid

PVTBAV05689-2 2 ug
EUR 427.2

pLenti-FOXM1 shRNA-2 Plasmid

PVTBAV08732-2 2 ug
EUR 427.2

pLenti-JUN shRNA-2 Plasmid

PVTBAV11741-2 2 ug
EUR 427.2

pLenti-LHX6 shRNA-2 Plasmid

PVTBAV12881-2 2 ug
EUR 427.2

pLenti-MAGEA3 shRNA-2 Plasmid

PVTBAV13661-2 2 ug
EUR 427.2

pLenti-RUNX3 shRNA-2 Plasmid

PVTBAV20583-2 2 ug
EUR 427.2

pLenti-Slc7a11 shRNA-2 Plasmid

PVTBAV21973-2 2 ug
EUR 427.2

pLenti-STAT3 shRNA-2 Plasmid

PVTBAV22921-2 2 ug
EUR 427.2

pLenti-XRCC5 shRNA-2 Plasmid

PVTBAV26238-2 2 ug
EUR 427.2

pET-dCas9-VP64-6xHis

PVT17702 2 ug
EUR 360

pET-6xHis-(-30)GFP

PVT17881 2 ug
EUR 409.2

pET- NLS- Cas9- 6xHis

PVT10639 2 ug
EUR 361.2

Recombinant Transmembrane Protease Serine 2 Protein, Partial

E80016
  • EUR 470.80
  • EUR 753.50
  • EUR 1824.90
  • 20 ul
  • 100 ul
  • 500 ul

ACE2, His-Tag Protein

E80019
  • EUR 612.70
  • EUR 1437.70
  • 20 ul
  • 100 ul

Mouse Anti-6xHIS Tag monoclonal antibody

CABT-BL8767 100ug
EUR 670.8

Anti-6xHIS Tag Antibody | CHIS-45A

CHIS-45A 1.0 mg
EUR 1142
Description:

Anti-6xHIS Tag Antibody | CHIS-45A | Immunology Consultants Laboratory

Host: Chicken

Format: Unconjugated AP

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | CHIS-45F

CHIS-45F 1.0 mg
EUR 1157
Description:

Anti-6xHIS Tag Antibody | CHIS-45F | Immunology Consultants Laboratory

Host: Chicken

Format: FITC Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | CHIS-45P

CHIS-45P 1.0 mg
EUR 1173
Description:

Anti-6xHIS Tag Antibody | CHIS-45P | Immunology Consultants Laboratory

Host: Chicken

Format: HRP Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | MHIS-45A

MHIS-45A 1.0 mg
EUR 1142
Description:

Anti-6xHIS Tag Antibody | MHIS-45A | Immunology Consultants Laboratory

Host: Mouse

Format: Unconjugated AP

Product Type: Primary Antibody

Antibody Clonality: Monoclonal

Anti-6xHIS Tag Antibody | RHIS-45A

RHIS-45A 1.0 mg
EUR 1142
Description:

Anti-6xHIS Tag Antibody | RHIS-45A | Immunology Consultants Laboratory

Host: Rabbit

Format: Unconjugated AP

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | RHIS-45B

RHIS-45B 1.0 mg
EUR 1157
Description:

Anti-6xHIS Tag Antibody | RHIS-45B | Immunology Consultants Laboratory

Host: Rabbit

Format: Biotin Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | RHIS-45F

RHIS-45F 1.0 mg
EUR 1157
Description:

Anti-6xHIS Tag Antibody | RHIS-45F | Immunology Consultants Laboratory

Host: Rabbit

Format: FITC Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | RHIS-45P

RHIS-45P 1.0 mg
EUR 1173
Description:

Anti-6xHIS Tag Antibody | RHIS-45P | Immunology Consultants Laboratory

Host: Rabbit

Format: HRP Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

pDONR223-CD73 Plasmid

PVTB00480-2 2 ug
EUR 427.2

Plasmid Midi Kit I

K1314-2
EUR 314.4

Plasmid Midi Kit II

K1315-2
EUR 314.4

Plasmid ezFilter Mega3 Kit

K1320-2
EUR 411.6

Plasmid ezFilter Mega6 Kit

K1321-2
EUR 444

Plasmid ezFilter Mega10 Kit

K1322-2
EUR 542.4

pCR4-TOPO-RNF135 Plasmid

PVTB01189-2 2 ug
EUR 427.2

pGEM-Ltf(Q25R) Plasmid

PVTB50084-2 2 ug
EUR 427.2

Anti-6xHIS Tag Antibody | CHIS-45A-Z

CHIS-45A-Z 0.1 mg
EUR 348
Description:

Anti-6xHIS Tag Antibody | CHIS-45A-Z | Immunology Consultants Laboratory

Host: Chicken

Format: Unconjugated AP

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | CHIS-45F-Z

CHIS-45F-Z 0.1 mg
EUR 363
Description:

Anti-6xHIS Tag Antibody | CHIS-45F-Z | Immunology Consultants Laboratory

Host: Chicken

Format: FITC Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | CHIS-45P-Z

CHIS-45P-Z 0.1 mg
EUR 379
Description:

Anti-6xHIS Tag Antibody | CHIS-45P-Z | Immunology Consultants Laboratory

Host: Chicken

Format: HRP Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | MHIS-45A-Z

MHIS-45A-Z 0.1 mg
EUR 316
Description:

Anti-6xHIS Tag Antibody | MHIS-45A-Z | Immunology Consultants Laboratory

Host: Mouse

Format: Unconjugated AP

Product Type: Primary Antibody

Antibody Clonality: Monoclonal

Anti-6xHIS Tag Antibody | RHIS-45A-Z

RHIS-45A-Z 0.1 mg
EUR 348
Description:

Anti-6xHIS Tag Antibody | RHIS-45A-Z | Immunology Consultants Laboratory

Host: Rabbit

Format: Unconjugated AP

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | RHIS-45B-Z

RHIS-45B-Z 0.1 mg
EUR 363
Description:

Anti-6xHIS Tag Antibody | RHIS-45B-Z | Immunology Consultants Laboratory

Host: Rabbit

Format: Biotin Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | RHIS-45F-Z

RHIS-45F-Z 0.1 mg
EUR 363
Description:

Anti-6xHIS Tag Antibody | RHIS-45F-Z | Immunology Consultants Laboratory

Host: Rabbit

Format: FITC Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Anti-6xHIS Tag Antibody | RHIS-45P-Z

RHIS-45P-Z 0.1 mg
EUR 379
Description:

Anti-6xHIS Tag Antibody | RHIS-45P-Z | Immunology Consultants Laboratory

Host: Rabbit

Format: HRP Conjugated

Product Type: Primary Antibody

Antibody Clonality: Polyclonal

Multi Fusion-Tagged recombinant Protein 52-Kda containing 16-tags (T-7, HSV, C-myc, VSV-G, Glu-Glu, V5, e-tag, Flag, S-tag, HA, KT3, E2, Au1, Au5, 6xHis-tags) for ELISA/Western

MFPM52-C 100 ul
EUR 343.2

ToxOut? Endofree Plasmid Midi Kit

K1328-2
EUR 248.4

ToxOut? Endofree Plasmid Maxi Kit

K1330-2
EUR 280.8

ToxOut? Endofree Plasmid Mega3 Kit

K1332-2
EUR 379.2

ToxOut? Endofree Plasmid Mega6 Kit

K1333-2
EUR 444

ToxOut? Endofree Plasmid Mega10 Kit

K1334-2
EUR 510

pMD19-T-LEO1(E225G) Plasmid

PVTB01141-2 2 ug
EUR 427.2

Nori® Human VEGF-C ELISA Kit (2 plates)

GR106472-2 2 x 96-well
EUR 998.4

Nori® Bovine PKA C ELISA Kit- 2 Plates

GR112034-2 2 x 96-well
EUR 998.4

Nori® Porcine PKA C ELISA Kit- 2 Plates

GR113039-2 2 x 96-well
EUR 998.4

Nori® Chicken PKA-C ELISA Kit- 2 Plates

GR114014-2 2 x 96-well
EUR 998.4

Recombinant TMPRSS2 Protein, Partial

E80017
  • EUR 423.50
  • EUR 660.00
  • EUR 2321.00
  • 20 ul
  • 100 ul
  • 1 ml

Recombinant Novel Coronavirus Spike Glycoprotein(S), Partial

E80018
  • EUR 388.30
  • EUR 860.20
  • EUR 4888.40
  • 20 ul
  • 100 ul
  • 1 ml

Express Plasmid Maxiprep Kit (25 min)

K1324-2
EUR 339.6

ToxOut? Endofree ezFilter Plasmid Midi Kit

K1329-2
EUR 248.4

ToxOut? Endofree ezfilter Plasmid Maxi Kit

K1331-2
EUR 280.8

ToxOut? Express Endofree Plasmid Midi Kit

K1335-2
EUR 280.8

ToxOut? Express Endofree Plasmid Maxi Kit

K1336-2
EUR 314.4

Plasmid ezFilter Midi Kit I, Centrifuge

K1316-2
EUR 314.4

Plasmid ezFilter Midi Kit II, Centrifuge

K1317-2
EUR 314.4

Express Plasmid Midiprep Kit (25 min)

K1323-2
EUR 314.4

pCDH-EF1-CymR-T2A-Puro (plasmid)

QM200PA-2 10 ug
EUR 716.4

pCDH-EF1-CymR-T2A-Neo (plasmid)

QM400PA-2 10 ug
EUR 697.2

Nori® Equine PKA C-alpha ELISA Kit- 2 Plates

GR106566-2 2 x 96-well
EUR 998.4

Nori® Human PKA C-alpha ELISA Kit- 2 Plates

GR111082-2 2 x 96-well
EUR 998.4

Nori® Bovine PKA C-alpha ELISA Kit- 2 Plates

GR112035-2 2 x 96-well
EUR 998.4

Nori® Porcine PKA C-alpha ELISA Kit- 2 Plates

GR113068-2 2 x 96-well
EUR 998.4

Nori® Chicken PKA C-alpha ELISA Kit- 2 Plates

GR114015-2 2 x 96-well
EUR 998.4

Monoclonal Anti-Poly-His (6xhis) (His-tag) IgG

HISP14-M 100 ug
EUR 578.4

Phospholipid transfer Antibody

20-abx110096
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Thermal Transfer Ribbon

HIS3233 EACH
EUR 139.08

Propane Transfer System

M-CEM-37015 1 UNIT
EUR 625
Description: Propane Transfer System

Nori® Human Angiopoietin-2 (ANG-2) ELISA Kit (2 plates)

GR106245-2 2 x 96-well
EUR 998.4

Nori Equine MMP-2/TIMP-2 Complex ELISA Kit (2 plates)

GR106502-2 2 x 96-well
EUR 998.4

2-Propyl-β-D-glucuronide, 2 mg

0904-2 2 mg
EUR 194.4

Emergence of Hypervirulent Carbapenem-Resistant Klebsiella pneumoniae Coharboring a bla NDM-1-Carrying Virulent Plasmid and a bla KPC-2-Carrying Plasmid in an Egyptian Hospital

The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) isolates in Egyptian hospitals has been reported. Nonetheless, the genetic foundation and evaluation of the plasmids related to carbapenem-resistant hypervirulent Okay. pneumoniae (CR-HvKP) in Egypt haven’t been introduced. Due to this fact, we tried to decipher the plasmid sequences which might be accountable for transferring the determinants of carbapenem resistance, significantly bla NDM-1 and bla KPC-2 Out of 34 Okay. pneumoniae isolates collected from two tertiary hospitals in Egypt, 31 had been CRKP. Entire-genome sequencing revealed that our isolates had been associated to 13 completely different sequence varieties (STs). Essentially the most prevalent ST was ST101, adopted by ST383 and ST11.

Amongst the CRKP isolates, one isolate named EBSI036 has been reassessed by Nanopore sequencing. Genetic setting evaluation confirmed that EBSI036 carried 20 antibiotic resistance genes and was recognized as a CR-HvKP pressure: it harbored 4 plasmids, particularly, pEBSI036-1-NDM-VIR, pEBSI036-2-KPC, pEBSI036-3, and pEBSI036-4. The 2 carbapenemase genes bla NDM-1 and bla KPC-2 had been situated on plasmids pEBSI036-1-NDM-VIR and pEBSI036-2-KPC, respectively.

The IncFIB:IncHI1B hybrid plasmid pEBSI036-1-NDM-VIR additionally carried some virulence elements, together with the regulator of the mucoid phenotype (rmpA), the regulator of mucoid phenotype 2 (rmpA2), and aerobactin (iucABCD and iutA). Thus, we set out on this examine to research in depth the genetic foundation of the pEBSI036-1-NDM-VIR and pEBSI036-2-KPC plasmids. We report a high-risk clone ST11 KL47 serotype of a CR-HvKP pressure remoted from the blood of a 60-year-old hospitalized feminine affected person from the intensive care unit (ICU) in a tertiary care hospital in Egypt, which confirmed the cohabitation of a novel hybrid plasmid coharboring the bla NDM-1 and virulence genes and a bla KPC-2-carrying plasmid.

IMPORTANCE CRKP has been registered within the essential precedence tier by the World Well being Group and has turn into a major menace to public well being. The emergence of CR-HvKP is of nice concern by way of each illness and remedy. In-depth evaluation of the carbapenemase-encoding and virulence plasmids could present perception into ongoing recombination and evolution of virulence and multidrug resistance in Okay. pneumoniae Thus, this examine serves to alert contagious illness clinicians to the presence of hypervirulence in CRKP isolates in Egyptian hospitals.

Expression of Bacillus amyloliquefaciens transglutaminase in recombinant E. coli underneath the management of a bicistronic plasmid system in DO-stat fed-batch bioreactor cultivations

We studied the expression of Bacillus amyloliquefaciens transglutaminase cloned in Escherichia coli BL21(DE3)pLysS harboring the plasmid pBAD/3C/bTGase, a bicistronic expression system, in bioreactor cultivation. Batch and fed-batch managed as DO-stat methods had been employed for the manufacturing of the recombinant enzyme. In 30 h-batch cultivations utilizing Terrific broth (TB), 6 g/L of biomass and three.12 U/mgprotein of transglutaminase exercise had been obtained. DO-stat fed-batch cultivations underneath the management of oxygen focus (DO-stat) utilizing TB as medium however fed with glucose allowed the increment in biomass formation (17.5 g/L) and enzyme exercise (6.43 U/mgprotein).

DO-stat fed-batch utilizing mineral medium (M9) and fed with glucose underneath the identical circumstances produced even increased enzymatic exercise (9.14 U/mgprotein). The pH impact was investigated, and the perfect enzymatic exercise might be noticed at pH 8. In all cultivations, the bicistronic system remained secure, with 100% of plasmid-bearing cells. These outcomes present that E. coli bearing bicistronic plasmid constructs to precise recombinant TGase might be cultivated in bioreactors underneath DO-stat fed-batch utilizing mineral medium and it’s a promising technique in future optimizations to supply this necessary enzyme.

Ceftazidime-Avibactam Resistance in Klebsiella pneumoniae Sequence Sort 11 Resulting from a Mutation in Plasmid-Borne bla kpc-2 to bla kpc-33, in Henan, China

Function: Carbapenem-resistant Klebsiella pneumoniae (CRKP) represents a major problem worldwide. Herein, we describe the evolution of ceftazidime-avibactam (CZA) resistance by sequencing scientific isolates from a affected person with CRKP an infection present process CZA remedy.

Sufferers and strategies: On this examine, six CRKP strains had been remoted from sputum and blood samples of a affected person with CRKP an infection after intracerebral hemorrhage. Two strains had been chosen for whole-genome evaluation.

Outcomes: Drug susceptibility testing confirmed that the MIC of CZA for CRKP strains remoted after 6 days of CZA remedy was 64-fold increased than that for 3 CRKP strains remoted earlier than CZA remedy (Four vs >256 μg/mL), whereas the MIC of imipenem and meropenem was 128-fold (>32 vs 0.25 μg/mL) and 16-fold (> 32 vs 2 μg/mL) decrease comparatively, respectively. Multilocus sequence typing confirmed that each one six CRKP strains remoted from the affected person had been ST11 and pulsed-field gel electrophoresis confirmed that they had been of the identical clone. Two strains had been chosen for whole-genome evaluation. The aspartic acid residue at place 179 within the Ω loop was changed by a tyrosine residue within the resistant pressure, and the plasmid carried a bla KPC-2 to bla KPC-33 mutation. The outcomes of the modified carbapenem inactivation methodology and the carbapenemase inhibitor enhancement and colloidal gold enzyme immunochromatographic assays for bla KPC-33 had been detrimental.

Conclusion: That is the primary report from Henan to point out that remedy with CZA for six days may cause mutations and alter the phenotype from CZA delicate to resistant. Due to this fact, routine testing for drug susceptibility and carbapenemase phenotypes must be carried out throughout remedy with CZA, and genotype dedication is crucial.

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC040958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF405S conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC050945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF405M conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC050945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF405M conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC050946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF405M conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC050946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF405M conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC050958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF405M conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC050958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF405M conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNCAP0945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNCAP0945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNCAP0946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNCAP0946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNCAP0958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNCAP0958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), Alkaline Phosphatase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNCB0945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), Biotin conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNCB0945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), Biotin conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNCB0946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), Biotin conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNCB0946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), Biotin conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNCB0958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), Biotin conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNCB0958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), Biotin conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNCP0945-250 250uL
EUR 459.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), PerCP conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNCP0946-250 250uL
EUR 459.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), PerCP conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNCP0958-250 250uL
EUR 459.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), PerCP conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNCR0945-250 250uL
EUR 459.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), RPE conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNCR0946-250 250uL
EUR 459.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), RPE conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNCR0958-250 250uL
EUR 459.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), RPE conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC940945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF594 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC940945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF594 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC940946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF594 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC940946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF594 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC940958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF594 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC940958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF594 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNCA0945-250 250uL
EUR 459.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), APC conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNCA0946-250 250uL
EUR 459.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), APC conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNCA0958-250 250uL
EUR 459.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), APC conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC810945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF680R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC810945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF680R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC810946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF680R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC810946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF680R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC810958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF680R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC810958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF680R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNUB0945-100 100uL
EUR 250.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), Concentration: 0.2mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNUB0945-500 500uL
EUR 549.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), Concentration: 0.2mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNUB0946-100 100uL
EUR 250.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), Concentration: 0.2mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNUB0946-500 500uL
EUR 549.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), Concentration: 0.2mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNUB0958-100 100uL
EUR 250.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), Concentration: 0.2mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNUB0958-500 500uL
EUR 549.6
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), Concentration: 0.2mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNCH0945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNCH0945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNCH0946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNCH0946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNCH0958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNCH0958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), Horseradish Peroxidase conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC880945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF488A conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC880945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF488A conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC880946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF488A conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC880946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF488A conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC880958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF488A conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC880958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF488A conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC680945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF568 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC680945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF568 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC680946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF568 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC680946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF568 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC680958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF568 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC680958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF568 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC470945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF647 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC470945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF647 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC470946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF647 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC470946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF647 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC470958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF647 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC470958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF647 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC400945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF640R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC400945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF640R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC400946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF640R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC400946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF640R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC400958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF640R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC400958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF640R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC430945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF543 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC430945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF543 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC430946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF543 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC430946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF543 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC430958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF543 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC430958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF543 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC550945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF555 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC550945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF555 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC550946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF555 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC550946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF555 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC550958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF555 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC550958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF555 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC610945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF660R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC610945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF660R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC610946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF660R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC610946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF660R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC610958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF660R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC610958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF660R conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC800945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF680 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC800945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF680 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC800946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF680 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC800946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF680 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC800958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF680 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC800958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF680 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC700945-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF770 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNC700945-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), CF770 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC700946-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF770 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNC700946-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), CF770 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC700958-100 100uL
EUR 238.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF770 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNC700958-500 500uL
EUR 652.8
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), CF770 conjugate, Concentration: 0.1mg/mL

Double Stranded DNA (dsDNA)(121-3) Antibody

BNUM0945-50 50uL
EUR 474
Description: Primary antibody against Double Stranded DNA (dsDNA)(121-3), 1mg/mL

Double Stranded DNA (dsDNA)(AE-2) Antibody

BNUM0946-50 50uL
EUR 474
Description: Primary antibody against Double Stranded DNA (dsDNA)(AE-2), 1mg/mL

Double Stranded DNA (dsDNA)(DSD/958) Antibody

BNUM0958-50 50uL
EUR 474
Description: Primary antibody against Double Stranded DNA (dsDNA)(DSD/958), 1mg/mL

Rat Double stranded DNA (dsDNA) Antibody ELISA Kit

abx159291-96tests 96 tests
EUR 1600.8

Human anti-double stranded DNA,dsDNA ELISA KIT

201-12-0487 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Rat anti-double stranded DNA,dsDNA ELISA KIT

CN-01623R1 96T
EUR 556.8

Rat anti-double stranded DNA,dsDNA ELISA KIT

CN-01623R2 48T
EUR 375.6

Human anti-double stranded DNA,dsDNA ELISA KIT

CN-03854H1 96T
EUR 580.8

Human anti-double stranded DNA,dsDNA ELISA KIT

CN-03854H2 48T
EUR 402

Mouse anti-double stranded DNA,dsDNA ELISA KIT

CN-02493M1 96T
EUR 586.8

Mouse anti-double stranded DNA,dsDNA ELISA KIT

CN-02493M2 48T
EUR 405.6

Mouse anti-double stranded DNA(dsDNA)ELISA Kit

GA-E0152MS-48T 48T
EUR 403.2

Mouse anti-double stranded DNA(dsDNA)ELISA Kit

GA-E0152MS-96T 96T
EUR 640.8

Rat anti-double stranded DNA(dsDNA)ELISA Kit

GA-E0398RT-48T 48T
EUR 447.6

Rat anti-double stranded DNA(dsDNA)ELISA Kit

GA-E0398RT-96T 96T
EUR 730.8

Human anti-double stranded DNA(dsDNA)ELISA Kit

GA-E0503HM-48T 48T
EUR 346.8

Human anti-double stranded DNA(dsDNA)ELISA Kit

GA-E0503HM-96T 96T
EUR 559.2

Human anti-double stranded DNA(dsDNA)ELISA Kit

QY-E02548 96T
EUR 433.2

Rat anti-double stranded DNA(dsDNA)ELISA Kit

QY-E11254 96T
EUR 433.2

Mouse anti-double stranded DNA(dsDNA)ELISA Kit

QY-E20118 96T
EUR 433.2

Mouse Double stranded DNA (dsDNA) Antibody IgG ELISA Kit

abx159292-96tests 96 tests
EUR 1431.6

Human Double stranded DNA (dsDNA) Antibody IgM ELISA Kit

abx159293-96tests 96 tests
EUR 1600.8

Human Double stranded DNA (dsDNA) Antibody IgG ELISA Kit

abx159294-96tests 96 tests
EUR 1093.2

Human anti-double stranded DNA,dsDNA IgM ELISA Kit

201-12-0600 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human anti-double stranded DNA,dsDNA IgA ELISA Kit

201-12-0602 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Rat anti-double stranded DNA(dsDNA) antibody ELISA Kit

CSB-E11195r-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat anti-double stranded DNA (dsDNA) antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat anti-double stranded DNA(dsDNA) antibody ELISA Kit

1-CSB-E11195r
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat anti-double stranded DNA(dsDNA) antibody in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit anti double stranded DNA,dsDNA IgG ELISA kit

E04A2063-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit anti double stranded DNA,dsDNA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit anti double stranded DNA,dsDNA IgG ELISA kit

E04A2063-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit anti double stranded DNA,dsDNA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit anti double stranded DNA,dsDNA IgG ELISA kit

E04A2063-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit anti double stranded DNA,dsDNA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit anti double stranded DNA,dsDNA IgM ELISA kit

E04A2064-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Rabbit anti double stranded DNA,dsDNA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit anti double stranded DNA,dsDNA IgM ELISA kit

E04A2064-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Rabbit anti double stranded DNA,dsDNA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit anti double stranded DNA,dsDNA IgM ELISA kit

E04A2064-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Rabbit anti double stranded DNA,dsDNA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig anti double stranded DNA,dsDNA IgG ELISA kit

E07A2063-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine anti double stranded DNA,dsDNA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig anti double stranded DNA,dsDNA IgG ELISA kit

E07A2063-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine anti double stranded DNA,dsDNA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig anti double stranded DNA,dsDNA IgG ELISA kit

E07A2063-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine anti double stranded DNA,dsDNA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig anti double stranded DNA,dsDNA IgM ELISA kit

E07A2064-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Porcine anti double stranded DNA,dsDNA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig anti double stranded DNA,dsDNA IgM ELISA kit

E07A2064-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Porcine anti double stranded DNA,dsDNA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig anti double stranded DNA,dsDNA IgM ELISA kit

E07A2064-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Porcine anti double stranded DNA,dsDNA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat anti double stranded DNA,dsDNA IgG ELISA kit

E06A2063-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat anti double stranded DNA,dsDNA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat anti double stranded DNA,dsDNA IgG ELISA kit

E06A2063-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat anti double stranded DNA,dsDNA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat anti double stranded DNA,dsDNA IgG ELISA kit

E06A2063-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Goat anti double stranded DNA,dsDNA IgG in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat anti double stranded DNA,dsDNA IgM ELISA kit

E06A2064-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Goat anti double stranded DNA,dsDNA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat anti double stranded DNA,dsDNA IgM ELISA kit

E06A2064-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Goat anti double stranded DNA,dsDNA IgM in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

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